Secondary analysis of the Game of Stones trial for men with obesity: Examining moderator effects and exploratory outcomes

Citation

Dombrowski SU, Hoddinott P, Macaulay L, O'Dolan C, Swingler J, Cotton S, Avenell A, Getaneh AM, Gray C, Hunt K, Kee F, Maclean A, McKinley MC, Torrens C & Turner K (2025) Secondary analysis of the Game of Stones trial for men with obesity: Examining moderator effects and exploratory outcomes. Obesity. https://doi.org/10.1002/oby.24316

Abstract
Objective To explore whether socio-economic, health and behavioural characteristics moderate effectiveness of a text message intervention with or without financial incentives versus a control group, and to examine differences in exploratory outcomes. Methods Three-group randomized trial including 585 men with obesity comparing daily automated behavioural text messages for 12-months alongside financial incentives; text messages alone; or a waiting list control. Moderator analyses examined percent weight change after 12 months for 9 socio-economic and 11 health factors. Exploratory outcomes included: self-reported physical activity, sedentary behaviour, smoking and alcohol behaviours, engagement in 15 weight management strategies, and weight-management related confidence. Results No moderator effects were found by any factors for either comparison versus control. There were no differences between groups for health behaviours. The texts with incentives group had higher levels of engagement in six strategies including weight goals, food changes and self-weighing, and higher levels of confidence compared to the control group. Conclusion No evidence of differential intervention effectiveness was found across socio-economic, health or wellbeing status. The texts and financial incentives group showed greater engagement in weight management and favourable changes in weight management confidence compared to the control group.

Notes
Additional authors: Marjon van der Pol, Graeme MacLennan

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