Healthcare use and costs of perinatal anxiety: a UK NHS perspective

Citation

Pisavadia K, Doungsong K, Ezeofor V, Spencer LH, Tuersley L, Best C, Meades R, Ayers S, Hutton U, Moran PM, Shakespeare J, Sinesi A, Edwards RT, MAP ALLIANCE study team & MAP ALLIANCE study team (2025) Healthcare use and costs of perinatal anxiety: a UK NHS perspective. BMC Health Services Research, 25, Art. No.: 1183. https://doi.org/10.1186/s12913-025-13318-z

Abstract
Background Perinatal anxiety is a significant public health issue with potential adverse outcomes for both mothers and their babies. This study provides a comprehensive analysis of the costs associated with health service use for women with and without perinatal anxiety in the UK National Health Service (NHS) at six and twelve months postpartum. This research is part of the MAP Alliance Study—a large programme of research on perinatal anxiety. Methods A cost of illness (COI) analysis was performed using a retrospective approach in which recorded data of self-reported health resource use was analysed. The COI analysis identified the different components of costs and the size of the contribution of each health resource and quantified the direct costs incurred by the NHS due to perinatal anxiety. Results Results found that women experiencing perinatal anxiety use healthcare services more frequently and incur higher healthcare costs compared to those without. At six months postpartum, the mean total healthcare cost per woman with perinatal anxiety was £1174 (95% CI: 1080.67, 1263.05) compared with £1046 (95% CI: 975.16, 1123.83) for women without. At twelve months postpartum, the mean total healthcare cost per woman with perinatal anxiety was £414 (95% CI: 347.76, 488.87) compared with £267 (95% CI: 226.06, 314.81) for women without. However, this cost difference between the two groups was not statistically significant (-£14; 95% CI: -161.88, 135.65, p = 0.808). Conclusion These findings underscore the economic impact of perinatal anxiety on healthcare systems and highlight the need for targeted interventions to improve care pathways for affected women. The results of this analysis have significant implications for public health policy, emphasising the importance of optimising perinatal mental health care pathways to reduce long-term costs and improve outcomes for women.

Keywords
Perinatal anxiety; Women; Birth; Pregnancy; Healthcare resource use; Health services; Cost of illness; Health economics

Notes
MAP ALLIANCE study team: Margaret Maxwell, Helen Cheyne, Kathryn Hollins, Fiona Alderdice, Amy Delicate, Jennifer Holly, Rafiyah Khan, Rachel Leonard, Debra Salmon & Lily Strange

Journal
BMC Health Services Research: Volume 25

• Pisavadia Et Al 2025c Published